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Conolidine’s analgesic outcomes stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors during the central anxious technique, conolidine modulates alternate molecular targets. A Science Advancements review located that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, wh